Karen Luise Lang

Karen Luise Lang – karenluise@gmail.com [Lattes]

MAROSTICA, LUCAS LOUREN?O ; DE BARROS, ANDR? LU?S BRANCO ; OLIVEIRA, JULIANA ; SALGADO, BRENO SOUZA ; CASSALI, GEOVANNI DANTAS ; LEITE, ELAINE AMARAL ; CARDOSO, VALBERT NASCIMENTO ; Lang, Karen Luise ; Caro, Miguel Soriano Balparda ; DUR?N, FERNANDO JAVIER ; Schenkel, Eloir Paulo ; DE OLIVEIRA, M?NICA CRISTINA ; SIM?ES, CL?UDIA MARIA OLIVEIRA . Antitumor effectiveness of a combined therapy with a new cucurbitacin B derivative and paclitaxel on a human lung cancer xenograft model. TOXICOLOGY AND APPLIED PHARMACOLOGY, v. 329, p. 272-281, 2017. (doi: j.taap.2017.06.007)
 
SILVA, I.T. ; GELLER, F. C. ; E. DUDEK, SABINE ; LANG, K. L. ; CARO, MIGUEL S.B. ; DURÁN, FERNANDO J. ; SCHENKEL, ELOIR P. ; SIMÕES, CLÁUDIA M.O. . Cytotoxic effects of natural and semisynthetic cucurbitacins on lung cancer cell line A549. Investigational New Drugs, p. 139-148, 2016. (doi: s10637-015-0317-4)
SILVA, I. T. ; CARO, M. S. B. ; DURAN, F. J. ; LANG, K. L. ; SIMOES, C. M. O. ; SCHENKEL, E. P. . In Vitro and In Vivo Antitumor Activity of a Novel Semisynthetic Derivative of Cucurbitacin B. Plos One, v. 10, p. e0117794, 2015. (doi: journal.pone.0117794)

MOROTTI, ANA L.M. ; LANG, KAREN L. ; CARVALHO, IVONE ; SCHENKEL, ELOIR P. ; BERNARDES, LÍLIAN S.C. . Semi-Synthesis of new glycosidic triazole derivatives of dihydrocucurbitacin B. Tetrahedron Letters, v. 56, p. 303-307, 2015. (doi: j.tetlet.2014.11.049)

MACHADO, V. R. ; LANG, K. L. ; DURAN, F. J. ; CABRERA, G. M. ; Palermo, Jorge Alejandro ; SCHENKEL, E. P. ; BERNARDES, L. S. C. . DI-HIDROCUCURBITACINA B: SEMI-SÍNTESE DE NOVOS DERIVADOS GLICOSILADOS. Química Nova (Online), v. 38, p. 37-41, 2015.
MAROSTICA, LUCAS LOURENÇO ; SILVA, IZABELLA THAIS ; KRATZ, JADEL M. ; PERSICH, LARA ; GELLER, FABIANA CRISTINA ; Lang, Karen Luise ; CARO, MIGUEL S.B. ; Durán, Fernando Javier ; Schenkel, Eloir Paulo ; Simões, Cláudia Maria Oliveira . Synergistic antiproliferative effects of a new cucurbitacin B derivative and chemotherapy drugs on lung cancer cell line A549. Chemical Research in Toxicology, v. 28, p. 1949-1960, 2015. (doi: acs.chemrestox.5b00153)
LANG, KAREN L.; SILVA, IZABELLA T. ; MACHADO, VANESSA R. ; ZIMMERMANN, LARA A. ; CARO, MIGUEL S.B. ; SIMÕES, CLÁUDIA M.O. ; SCHENKEL, ELOIR P. ; DURÁN, FERNANDO J. ; BERNARDES, LÍLIAN S.C. ; DE MELO, EDUARDO B. . Multivariate SAR and QSAR of cucurbitacin derivatives as cytotoxic compounds in a human lung adenocarcinoma cell line. Journal of Molecular Graphics & Modelling, v. 48, p. 70-79, 2014. (doi: j.jmgm.2013.12.004)
ASSINI, F. ; FABRICIO, E. J. ; LANG, K. L. . Efeitos farmacológicos do extrato aquoso de Solidago chilensis Meyen em camundongos. Revista Brasileira de Plantas Medicinais (Impresso), v. 15, p. 130-134, 2013. (doi: S1516-05722013000100018)
LANG, K. L.; DEAGOSTO, E. ; Zimmermann, Lara Almida ; MACHADO, V. R. ; BERNARDES, L. S. C. ; SCHENKEL, E. P. ; DURAN, F. J. ; Palermo, Jorge Alejandro ; ROSSINI, C. . Chemical Modification Produces Species-Specific Changes in Cucurbitacin Antifeedant Effect. Journal of Agricultural and Food Chemistry, v. 61, p. 5534-5539, 2013. (doi: jf4002457)
 
M.O. SIMOE, CLAUDIA ; SILVA, I.T. ; R. TEIXEIR, MARINA ; L. LANG, KAREN ; R. GUIMARA, TATIANA DA ; E. DUDEK, SABINE ; J. DURAN, FERNANDO ; LUDWIG, STEPHAN ; S.B. CARO, MIGUEL ; P. SCHENKE, ELOIR . Proliferative Inhibition and Apoptotic Mechanism on Human Non-small-cell Lung Cancer (A549 Cells) of a Novel Cucurbitacin from Wilbrandia ebracteata Cogn. International Journal of Cancer Research (Print), v. 9, p. 54-68, 2013. (doi: ijcr.2013.54.68)
Lang, Karen Luise; Silva, Izabella Thaís ; Zimmermann, Lara Almida ; Machado, Vanessa Rocha ; Teixeira, Marina Rodrigues ; Lapuh, María Ivana ; Galetti, Mariana Alejandra ; Palermo, Jorge Alejandro ; Cabrera, Gabriela Myriam ; Bernardes, Lílian Sibelle Campos ; Simões, Cláudia Maria Oliveira ; Schenkel, Eloir Paulo ; Caro, Miguel Soriano Balparda ; Durán, Fernando Javier . Synthesis and cytotoxic activity evaluation of dihydrocucurbitacin B and cucurbitacin B derivatives. Bioorganic & Medicinal Chemistry (Print), v. 20, p. 3016-3030, 2012. (doi: j.bmc.2012.03.001)
Baratto, Leopoldo ; Lang, Karen Luise ; Vanz, Danielli Cássia ; Reginatto, Flávio Henrique ; Oliveira, Jorge Barcelos ; Falkenberg, Miriam . Investigação das atividades alelopática e antimicrobiana de Mikania laevigata (Asteraceae) obtida de cultivos hidropônico e tradicional. Revista Brasileira de Farmacognosia (Impresso), v. 18, p. 577, 2008. (doi: S0102-695X2008000400014)
MORITZ, M. I. G. ; LANG, K. L. ; Baratto, L. ; CARO, M. S. B. ; FALKENBERG, M. ; SCHENKEL, E. P. . Identification of undeclared synthetic drugs in herbal products commercialized in Brazil: the ?Indiano Talun? case. Acta Farmacéutica Bonaerense, v. 27, p. 274-279, 2008.
GOULART, S. ; MORITZ, M. I. G. ; LANG, K. L. ; DE LIZ, R. ; SCHENKEL, E. P. ; FRÖDE, T. S. . Anti-inflammatory evaluation of Solidago chilensis Meyen in a murine model of pleurisy. Journal of Ethnopharmacology, v. 113, p. 346-353, 2007. (doi: j.jep.2007.07.003)
LANG, K. L.; PALERMO, J. ; FALKENBERG, M. ; SCHENKEL, E. P. . Steroids from the red alga Acanthophora spicifera. Biochemical Systematics and Ecology, v. 35, p. 805-808, 2007. (doi: j.bse.2007.04.001)
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